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A Study Finds that a Recently Approved Combination Treatment May Help Some Patients Achieve Greater Reductions in Their Blood Pressure


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(OPEN):
NEARLY ONE-THIRD OF ADULTS IN THE U-S HAVE HYPERTENSION--OR HIGH BLOOD-PRESSURE--WHICH CAN LEAD TO OTHER, MORE-SERIOUS CARDIOVASCULAR-RISKS--SUCH AS HEART-ATTACK AND STROKE.  SCIENTISTS CONTINUE TO STUDY EFFECTIVE COMBINATION-TREATMENTS THAT CAN HELP APPROPRIATE-PATIENTS LOWER THEIR BLOOD-PRESSURE NUMBERS.  A STUDY IN A RECENT ISSUE OF THE "AMERICAN HEART ASSOCIATION"-JOURNAL "HYPERTENSION" FOUND THAT "EDARBYCLOR" ("AZILSARTAN MEDOXOMIL" AND "CHLORTHALIDONE") MAY HELP SOME PATIENTS EFFECTIVELY REACH THEIR BLOOD-PRESSURE TARGETS.  DOCTOR MICHAEL WEBER IS A STUDY-AUTHOR...

(WEBER):
"
MANY PATIENTS WILL REQUIRE MORE THAN ONE MEDICATION, EACH DAY, TO HELP MANAGE THEIR HYPERTENSION.  THIS STUDY FOUND THAT PATIENTS WHO RECEIVED A COMBINATION-TREATMENT CALLED 'EDARBYCLOR' ACHIEVED GREATER BLOOD-PRESSURE REDUCTIONS THAN ANOTHER COMBINATION-MEDICATION."

(CLOSE--INCLUDING FULL "IMPORTANT SAFETY INFORMATION"):
"EDARBYCLOR"--THE COMBINATION OF "EDARBI" ("AZILSARTAN MEDOXOMIL") AND THE DIURETIC "CHLORTHALIDONE"--WAS APPROVED BY THE F-D-A IN DECEMBER.  BOTH "EDARBI" AND "EDARBYCLOR" ARE INDICATED FOR THE TREATMENT OF HYPERTENSION IN ADULTS, TO LOWER BLOOD-PRESSURE.  VISIT "EDARBI"-DOT-COM; THAT'S "E-D-A-R-B-I"-DOT-COM.

"EDARBI" AND "EDARBYCLOR" ARE PRESCRIPTION-MEDICINES USED TO TREAT HIGH BLOOD-PRESSURE (HYPERTENSION).  YOUR DOCTOR MAY PRESCRIBE OTHER MEDICINES FOR YOU TO TAKE ALONG WITH "EDARBI" OR "EDARBYCLOR", TO TREAT YOUR HIGH BLOOD-PRESSURE.  "EDARBYCLOR" IS USED WHEN ONE MEDICINE IS NOT ENOUGH--OR AS THE FIRST MEDICINE--IF YOUR DOCTOR DECIDES YOU ARE LIKELY TO NEED MORE THAN ONE MEDICINE.  MEDICINES THAT LOWER YOUR BLOOD-PRESSURE MAY LOWER YOUR CHANCES OF HAVING A STROKE OR HEART-ATTACK--BUT THEY DON'T WORK ALONE.  IT SHOULD BE PART OF A COMPLETE TREATMENT-PLAN.

IMPORTANT SAFETY INFORMATION

WARNING:  "EDARBI" AND "EDARBYCLOR" CAN CAUSE HARM OR DEATH TO YOUR UNBORN-BABY.  IF YOU BECOME PREGNANT WHILE TAKING "EDARBI" OR "EDARBYCLOR", TELL YOUR DOCTOR RIGHT AWAY.  IF YOU PLAN TO BECOME PREGNANT, TALK TO YOUR DOCTOR ABOUT OTHER TREATMENTS TO LOWER BLOOD-PRESSURE.

BEFORE TAKING "EDARBI" OR "EDARBYCLOR", TELL YOUR DOCTOR IF YOU ARE BREASTFEEDING OR PLAN TO BREASTFEED.  DISCUSS WITH YOUR DOCTOR OTHER WAYS TO LOWER YOUR BLOOD-PRESSURE.  IT IS NOT KNOWN IF "EDARBYCLOR" PASSES INTO BREAST-MILK.  YOU AND YOUR DOCTOR SHOULD DECIDE IF YOU WILL TAKE "EDARBI" OR "EDARBYCLOR" AND BREASTFEED.  YOU SHOULD NOT DO BOTH.

DO NOT TAKE "EDARBYCLOR" IF YOU MAKE LESS URINE BECAUSE OF KIDNEY-PROBLEMS ("ANURIA").

TELL YOUR DOCTOR ABOUT ALL YOUR MEDICAL-CONDITIONS--INCLUDING IF YOU HAVE HEART-PROBLEMS OR STROKE, HAVE GOUT, OR HAVE LIVER- OR KIDNEY-PROBLEMS.  KIDNEY-PROBLEMS MAY BECOME WORSE IN PEOPLE THAT ALREADY HAVE KIDNEY-DISEASE.  IF YOU HAVE KIDNEY-PROBLEMS, YOU MAY NEED BLOOD-TESTS--AND YOUR DOCTOR MAY NEED TO LOWER YOUR DOSE, OR MAY NEED TO STOP TREATMENT WITH "EDARBYCLOR".

TELL YOUR DOCTOR ABOUT ALL THE MEDICINES YOU TAKE--INCLUDING PRESCRIPTION- AND NONPRESCRIPTION-MEDICINES, VITAMINS, AND HERBAL SUPPLEMENTS.  ESPECIALLY TELL YOUR DOCTOR IF YOU TAKE OTHER MEDICINES TO TREAT YOUR HIGH BLOOD-PRESSURE OR HEART-PROBLEM; WATER-PILLS (DIURETICS); LITHIUM--A MEDICINE USED TO TREAT SOME TYPES OF DEPRESSION; OR "DIGOXIN".

"EDARBI" AND "EDARBYCLOR" MAY CAUSE SERIOUS SIDE-EFFECTS, INCLUDING LOW BLOOD-PRESSURE (HYPOTENSION)--WHICH MAY CAUSE YOU TO FEEL FAINT AND DIZZY.  VOMITING AND DIARRHEA, A LOW-SALT DIET, OR NOT DRINKING ENOUGH FLUID CAN ALSO LEAD TO LOW BLOOD-PRESSURE.

IF YOU FEEL FAINT OR DIZZY, LIE DOWN AND CALL YOUR DOCTOR RIGHT AWAY.  IF YOU PASS OUT (FAINT), HAVE SOMEONE CALL YOUR DOCTOR OR GET MEDICAL-HELP.  STOP TAKING "EDARBYCLOR".

IF YOU HAVE FLUID- AND BODY-SALT- (ELECTROLYTES) PROBLEMS, TELL YOUR DOCTOR IF YOU EXPERIENCE ANY OF THE FOLLOWING SYMPTOMS: DRY MOUTH, CONFUSION, THIRST, LACK-OF-ENERGY/WEAKNESS, DROWSINESS, PASSING VERY LITTLE URINE OR PASSING LARGE AMOUNTS OF URINE, SEIZURES, MUSCLE-PAIN/CRAMPS, RESTLESSNESS, MUSCLE-TIREDNESS (FATIGUE), FAST OR ABNORMAL HEARTBEAT, NAUSEA AND VOMITING, AND CONSTIPATION.

PEOPLE WHO HAVE INCREASED LEVELS OF URIC-ACID IN THE BLOOD MAY DEVELOP GOUT.  IF YOU ALREADY HAVE GOUT, TELL YOUR DOCTOR ABOUT WORSENING OF YOUR GOUT-SYMPTOMS.  IN CLINICAL STUDIES, THE MOST-COMMON SIDE-EFFECT SEEN WITH "EDARBI" WAS DIARRHEA.

IN CLINICAL STUDIES, THE SIDE-EFFECTS SEEN WITH "EDARBYCLOR" INCLUDED DIZZINESS AND TIREDNESS.

FOR FURTHER INFORMATION, PLEASE TALK TO YOUR HEALTHCARE-PROFESSIONAL, SEE FULL "PRESCRIBING INFORMATION" FOR "EDARBI" AND "EDARBYCLOR", AND VISIT "EDARBI"-DOT-COM; THAT'S "E-D-A-R-B-I"-DOT-COM.

YOU ARE ENCOURAGED TO REPORT NEGATIVE SIDE-EFFECTS OF PRESCRIPTION-DRUGS TO THE F-D-A.  VISIT W-W-W-DOT-"F-D-A"-DOT-GOV-SLASH-"MED-WATCH"--OR CALL 1-800-"F-D-A"-1088.



Copyright 2012 North American Network, Inc.

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